The relationship between lung cancer and silicosis or exposure to silica: meta-analysis of the medical literature Abstract Despite significant efforts to limit exposure to silica, the CSST recognized 494 new cases of silicosis in workers between 1988 and 2003 inclusively. Occupational lung disease committees are admitting the existence of a relationship between silica exposure and certain cases of lung cancer. This acknowledgement, as well as the question of cases of primary lung cancer in workers exposed to crystalline silica but who do not present signs of silicosis, is not however unanimously accepted by pneumologists interested in occupational health and safety. Analysis of the medical literature on the subject suggests that there is an increased risk of death due to lung cancer in silicotic people. The data published to date also suggest that silica exposure represents a low risk factor for lung cancer at exposure concentrations that exceed the permitted limit based on North American standards. These results agree with the conclusions of the International Agency for Research on Cancer (IARC), while qualifying them. Produced Under this Project Scientific Reports Silicosis, silica and lung cancer: meta-analysis of the medical literature Research Report: R-403 Scientific Publications Meta-analysis of silicosis and lung cancerLacasse Y., Martin S., Simard S., Desmeules M.Source : Scandinavian Journal of Work Environment and Health, vol. 31, no 6, 2005, p. 450-459 Additional Information Type: Project Number: 0099-1630 Status: Completed Year of completion: 2004 Research Field: Chemical and Biological Hazard Prevention Team: Yves Lacasse (Université Laval)Bruno Raby (Université Laval)Marc Desmeules (Université Laval)