Effects of exposure peaks on styrene neurotoxicity in the Fibreglass-Reinforced Plastics Sector. Phase 1 Abstract One of the tasks of workers in the fibreglass-reinforced plastics industry is to spread resin on large surfaces. Such an operation involves noncontinuous exposure to various chemical substances, including styrene. The researchers wanted to characterize the true exposure profiles of the workers in the companies as well as determine whether this solvent caused effects on the nervous systems of people exposed to experimentally-generated concentration peaks. The results show that the concentrations of the exposure peaks are up to 16 times higher than the average value, and that in some cases they exceed the Québec standard. They also reveal that when the experiments are carried out under controlled conditions, the nervous system is not affected by styrene if its concentration remains within the prescribed standards. It remains to be verified whether these results would be different in workplaces. Produced Under this Project Scientific Reports Effects of concentration peaks on styrene neurotoxicity in the fibreglass-reinforced plastics sector - Phase 1 Research Report: R-309 Simplified Articles Les pics de concentration du styrène sont-ils dangereux ?Industrie du plastique renforcé Volume 24, n0 1 Scientific Publications L’exposition des travailleurs aux pics de concentration de styrène dans l’industrie de fabrication de plastique renforcéThuot R., Vyskocil A., Turcot A., Gérin M., Viau C.Source : in Colloque annuel du CIRTOX (31 mai, 2001 : Montréal, Canada), 2001 Évaluation de l’exposition des travailleurs aux pics de concentration de styrène dans l’industrie de fabrication de plastique renforcéThuot R., Vyskocil A., Gérin M., Viau C., Turcot A., Rossner A., Nadeau J. G., Jacob M., Massicot C., Larouche J.-Y.Source : in D'un riche passé @ un avenir prometteur : 23e Congrès de l'Association québécoise pour l'hygiène, la santé et la sécurité du travail / AQHSST, (23e : 9-11 mai, 2001 : Hull, Canada), 2001, p. 131-134Effets des pics de concentrations sur la neurotoxicité du styrène chez des volontairesVyskocil A., Ska B., Tardif R., Carrier G., Thuot R., Viau C.Source : in La prévention : une démarche de qualité : Congrès de l'Association québécoise pour l'hygiène, la santé et la sécurité du travail / AQHSST, (24e : 8-10 mai, 2002 : Saint-Sauveur, Canada), 2002Effects of peak concentration on the neurotoxicity of styrene in volunteersSka B., Vyskocil A., Tardif R., Carrier G., Tuot R., Muray K., Viau C.Source : Human and Experimental Toxicology, vol. 22, no 8, 2003, p. 407-415Exposition à des pics de concentration de styrène dans l’industrie québécoise du plastique armé de fibre de verreVyskocil A., Viau C., Thuot R., Turcot A., Gérin M.Source : Travail et santé, vol. 18, 2002, p. S7–S11Effets of peak concentrations on the neurotoxicity of styrene in volunteersSka B., Vyskocil A., Tardif R., Carrier G., Thuot R., Viau C.Source : Toxicological Sciences, vol. 66, no 1, 2002, p. S 253Peak exposures in Quebec fibreglass reinforced plastic industryVyskocil A., Thuot R., Turcot A., Gérin M., Viau C.Source : in Epidemiology and Practice : 2001 Conference on Exposure Assessment (June 10-13, 2001 : Göteborg, Sweden). Arbete Och Hälsa, 2001, no 10Effect of peak exposure on the biological monitoring of exposure to styrene in volunteerTardif R., Vyskocil A., Charest-Tardif G., Ska B., Carrier G., Thuot R., Viau C.Source : in Eurotox 2002 : 40e congrès de la société européenne de toxicologie (15-18 septembre 2002 : Budapest, Hongrie), 2002Performance of small evacuated canisters equipped with a novel flow controller for the collection of personal air samplesRossner A., Warner S. D., Vyskocil A., Tardif R., Farant J. P.Source : Journal of Occupational and Environmental Hygiene, vol. 1, no 3, 2004, p. 173-181Physiologically based toxicokinetic modeling approach for the prediction of the blood and brain styrene concentration in workers exposed to peak styrene concentrationMuray K., Tardif R., Thuot R., Charest-Tardif G., Viau C., Vyskocil A.Source : in X2004 "Exposure Assessment in a Changing Environment" (June 16-18, 2004 : Utrecht, The Netherlands), 2004, p. 59 Additional Information Type: Project Number: 0098-0150 Status: Completed Year of completion: 2002 Research Field: Chemical and Biological Hazard Prevention Team: Adolf Vyskocil (Université de Montréal)Claude Viau (Université de Montréal)Michel Gérin (Université de Montréal)Robert Tardif (Université de Montréal)Gaétan Carrier (Université de Montréal)Bernadette Ska (Institut universitaire de gériatrie de Montréal)Jean-Pierre Farant (Université McGill)Alice Turcot (Direction régionale de santé publique)