Abstract

Although many chemicals are know to be absorbed through the skin and the general parameters influencing this phenomenon have been identified, the quantitative importance of skin absorption and the work conditions under which it becomes important remain unknown.

A comprehensive and critical literature review will be performed, describing the general mechanisms underlying skin absorption, the forms (vapour, liquid, semi-solid) in which contaminants can cross the skin, the quantitative importance of skin absorption will be evaluated, and typical work conditions favouring skin absorption.

A concise and practical guide designed for members of the prevention network will be produced, containing qualitative and quantitative data on the skin absorption of as many of the major occupational chemical contaminants as possible.