4,4'-Methylene dianiline

According to Decree 280-2024 published on February 28, 2024, in the Gazette officielle du Québec, the amendment to the Appendix 1 of the Regulation respecting occupational health and safety (RSST, RLRQ, c. S-2.1, r. 13) will come into force on March 14, 2024. These regulatory changes have not yet been incorporated into the current Substance Data Sheets of the Sampling Guide for Air Contaminants in the Workplace. An update is currently underway and will be available as soon as possible. Consequently, the information contained in the data sheets of substances modified or added in Decree 280-2024 is partially inaccurate or incomplete. Please consult our infoLABO (in French only) for more details. Please contact our client service: [email protected] for further information.

4,4'-Methylene dianiline

French name in the regulation: Diamino-4,4' diphénylméthane

CAS : 101-77-9

Synonyms: Méthylène-4,4' dianiline

Exposure Standards in RROHS regulation

Permissible exposure values (PEV)

	ppm	mg/m³	f/cc	Notes
TWAEV	0,1	0,81	-	-
STEV	-	-	-	-
Ceiling	-	-	-	-

Carcinogenicity	C2	Sensitizer
Simple asphyxiant		Percutaneous
Prohibited use		Prohibited recirculation
Minimum exposure		Explosion hazard
Ototoxic

TWA adjustment for unusual work schedules

III : Weekly adjustment

CNESST – Toxicological Index Service

Consult REPTOX file: 4,4'-Methylene dianiline

Analysis:

Diamino-4,4' diphénylméthane

Recommended method by the IRSST:

Method: NIOSH - 5029

Sampling protocol

Sampling device: Glass fiber filter impregnated with sulfuric acid
Parameters:
Flow rate: 1-2 L/min
TWA sampling volume: 1000 L
STEL sampling volume: -
Remarks: Immediately after sampling, transfer the filter to a vial containing a reactive solution. Contact the IRSST before sampling.

Analytical protocol

Principle: High performance liquid chromatography with UV detection (HPLC-UV)

Reference

NIOSH Manual of Analytical Methods, 4th ed. Method 5029 : 4,4'-Dimethylenedianiline, 1994.